Itching is the most common complaint in dermatology outpatient clinics. It is an unpleasant subjective feeling that stimulates the desire to scratch. A survey data on the skin condition of 4994 patients showed that the prevalence of pruritus in patients with skin diseases was 54.4%. CBD help with Acne and Itchy Skin the main symptoms of many skin diseases, and relieving itching is an important part of skin disease treatment.
Skin diseases are not big or small, and topical ointment and avoiding irritation are typical treatment methods. When symptoms are severe, it is also common to use multiple drugs in synergy. However, most skin problems are recurring and distressing due to certain triggers, such as stress or illness. When conventional treatments fail to resolve skin concerns, you need new alternatives.
CBD Anti-Inflammatory Properties Relieve Skin Conditions
A medical report published in 2018 summarized the potential benefits of CBD, and by pooling research data, researchers found that CBD may help treat skin conditions.
The anti-inflammatory properties of CBD can provide relief from a variety of skin conditions, including eczema. In past studies, researchers have explored the use of CBD in the treatment of acne, dermatitis, eczema, psoriasis, and a variety of other skin conditions, and findings have shown that CBD has anti-inflammatory properties and interacts with cannabinoid receptors to produce Various physiological effects that help regulate pain and itching. These properties and interactions help suppress sebum production, and reduce acne, thereby helping treat acne and fight inflammation to reduce irritation. In addition, CBD can be used to treat allergic contact dermatitis, atopic dermatitis and psoriasis – CBD may be beneficial in psoriasis treatment by inhibiting the proliferation of keratogenic cells in certain cell populations.
Mechanism
The endocannabinoid system (ECS) regulates a variety of physiological processes, including the growth and differentiation of skin cells. One study explored the effects of CBD on human sebaceous gland function and determined it to be a highly potent sebum inhibitor. Administration of CBD to cultured human sebocytes and human skin organ cultures inhibited the adipogenic effects of multiple compounds, including the binding of arachidonic and linoleic acids to testosterone, and by activating the transient receptor potential vanilloid-4 ( trpv4) ion channel inhibits sebocyte proliferation. Activation of TRPV4 interferes with the progenitor Erk1/2-map pathway, resulting in downregulation of nuclear receptor-interacting protein-1 (Nrip1), which in turn affects glucose and lipid metabolism, thereby inhibiting adipogenesis in sebocytes.
CBD has complex anti-inflammatory effects related to inhibition of arachidonic acid release and inhibition of cyclooxygenase COX-2, both of which are associated with the development of inflammation. Arachidonic acid can be converted into various metabolites in the body, which can mediate certain inflammatory responses; when the body encounters physical, chemical and biological stimuli, COX-2 is produced to mediate inflammatory responses.
CBD Provides Natural Relief for Itching and Irritation
Another group of studies found that CBD may help treat itchy skin. Much research has been done on the potential benefits of cannabinoids in skin diseases, the earliest from Henry Granger Piffard, MD, PhD (1842-1910), one of the founders of American dermatology. Dr Piffard, who wrote the first textbook on therapeutic dermatology, states: “Taking a CBD capsule at bedtime can sometimes relieve the unbearable itching of eczema.” Cannabinoids can be seen as having a powerful antipruritic effect.
In this study, researchers found that activation of the cannabinoid type 1 receptor (CB1) reduced itching by up to 86.5% without major side effects. The study involved the use of a topical cream containing cannabinoids that patients applied twice a day for three weeks. The results showed that pruritus was relieved in most patients. The study also highlights the anti-inflammatory properties of CBD, which can help reduce irritation from contact dermatitis or itching, a relief that can also help reduce symptoms associated with other skin conditions, allowing patients to avoid itching and exacerbations.
Summary
In past studies, researchers have explored the use of CBD in the treatment of acne, dermatitis, eczema, psoriasis and a variety of other skin conditions, and the results have shown that CBD has anti-inflammatory, lipid-suppressing, anti-proliferative properties that help relieve various This skin condition is a promising treatment for skin diseases.
