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Sunday, September 24, 2023

How CBD Helps In The Treatment Of Arrhythmia 

Arrhythmia and its symptoms.

An arrhythmia (also called arrhythmia) is a problem with the rate or rhythm of heartbeats. In an arrhythmia, the heart may beat too fast, too slow, or irregularly.

In healthy adults, the heart beats regularly at a rate of 60 to 100 times per minute. However, a sudden increase in stress, problems with the heart’s electrical signals, blood imbalances, and medications can all lead to changes in heart tissue, resulting in an irregular heartbeat.

Arrhythmias can be categorized by their effect on heart rate, with bradycardia referring to a heart rate below 60 beats per minute and tachycardia referring to a heart rate above 100 beats per minute.

Tachycardia or tachycardia is divided into supraventricular and ventricular arrhythmias.

Supraventricular arrhythmias begin in the atria (upper chambers of the heart) or at the entrance to the lower chambers. In this case, the upper and lower cavities sometimes have irregular rhythms.

Atrial fibrillation, atrial flutter, and paroxysmal supraventricular tachycardia (excessive heart rate caused by electrical signals in the upper and lower chambers) are supraventricular arrhythmias.

On the other hand, ventricular tachycardia is a steady but rapid beating of the ventricles which can last for a few seconds. This type of tachycardia usually does not cause serious heart problems.

However, if the ventricular arrhythmia persists for more than a few seconds, it can lead to a more serious condition, such as ventricular fibrillation.

Ventricular fibrillation occurs when the irregular electrical impulse causes the ventricles to contract instead of beating normally. This type of arrhythmia can cause cardiac arrest or heart failure.

Symptoms of arrhythmia include:

  • fast or slow heartbeat
  • Skipping heartbeat or palpitations
  • Dizziness or dizziness
  • Source
  • breathing difficulties
  • Sweat

Arrhythmia is often treated with lifestyle changes, such as stress management, maintaining a healthy weight, and physical activity.

Some doctors advise people to take anti-arrhythmic drugs, such as beta-blockers (to treat high blood pressure or high blood pressure), adenosine (to slow heart rate), blood thinners (to prevent blood clots), etc.

CBD and its benefits

Cannabidiol (CBD) is one of the botanical or natural components of the hemp plant. Hemp is a variety of cannabis plants low in THC but rich in CBD.

CBD is not psychoactive or addictive, unlike THC (tetrahydrocannabinol), which provides a euphoric effect. CBD oil is the typical form of CBD extract.

Phytocannabinoids (the cannabis plant) interact with the human endocannabinoid system (ECS). The ECS plays a vital role in the development of the central nervous system (CNS), subjective and environmental insults, and synaptic plasticity.

Although CBD and ECS, CB1, and CB2 receptors do not bind to a significant extent, one study found that CBD’s actions can be attributed to inhibition of anandamide breakdown or CBD’s antioxidant activity.

Anandamide is a fatty acid neurotransmitter that acts as a messenger molecule. It plays a role in pain, depression, memory, appetite, and fertility.

Research also suggests that CBD may induce protective effects that can help counteract the harmful effects of THC.

CBD is believed to have potential therapeutic benefits in treating various diseases and conditions.

Neuroprotective properties, chronic pain relief, anti-inflammatory properties, and anti-anxiety properties are some of the purported benefits of CBD.

An animal study examining CBD’s neuroprotective properties found that CBD can reduce both the number of vital neurons and degenerate neurons in newborn piglets suffering from hypoxia (a condition in which the body is deprived of an adequate supply of oxygen) and obstruction of the carotid artery. arteries (hypoxia-ischemia).

The same study also suggested that CBD administration may be linked to beneficial hemodynamic, cardiac, and ventilatory effects.

Another study in diabetic mouse models showed that CBD treatment could reduce neurotoxicity, inflammation, and breakdown of the blood-retinal barrier.

The anti-inflammatory characteristics of CBD were demonstrated in a study with human sebocytes (sebum-producing cells). The results suggest that CBD has potential benefits in treating acne vulgaris.

Additionally, a study has suggested that CBD may help fight cardiovascular disorders by reducing oxidative stress, fibrosis, and cell death.

CBD and arrhythmia: what the research says

According to a study published in the British Journal of Pharmacology, drastic administration of cannabidiol or CBD suppressed irregular heartbeats caused by ischemia-induced heart arrhythmias (insufficient blood supply to the heart) in an animal model. This finding suggests that CBD can protect the heart.

The study also found that CBD reduced tissue death due to insufficient blood supply (heart attack) before reperfusion.

The American Heart Association describes ischemia as a condition characterized by restricted or reduced blood flow (which also restricts oxygen flow).

In the same study, irregular heartbeats during ischemia were monitored before periods of CBD infusion (the passage of fluid through the circulatory system).

The size of the heart attack (a localized area of ​​dead tissue) or blockage of blood supply and cell damage in the heart has also been examined by drawing blood from the arteries.

The researchers also found the following:

Cannabidiol reduced the incidence of arrhythmias caused by decreased blood flow or ischemia.

CBD reduced heart attacks or the size of damaged tissue when cannabis was administered before ischemia.

The effect of CBD was dose-dependent.

CBD can help prevent ventricular arrhythmia, which is characterized by an irregular heartbeat that occurs in the ventricles, or chambers, of the heart.

According to an article published by the University of Rochester Medical Center, due to long-term stress, high blood cortisol levels can increase blood cholesterol, blood pressure, triglycerides, and blood sugar. These are common risk factors for arrhythmias and other heart diseases.

Meanwhile, CBD has been shown to have anti-anxiety properties that can help combat stress.

Published in the Neurotherapeutics Journal, a 2015 review of 49 studies noted the effectiveness of CBD in reducing anxiety behaviors associated with multiple disorders.

In some cases that contribute to the development of ventricular tachycardia, open-heart surgery may be necessary. An example of such a situation is when there is a blockage in the blood vessels.

After surgery or a heart attack, a person may experience a loss of appetite due to surgical pain, which can eventually lead to low calcium and potassium levels, delaying long-term recovery. Electrolyte imbalances can also predispose an individual to arrhythmias.

Fortunately, when it comes to pain relief, CBD can be beneficial. A study published in Chemistry & Biodiversity showed that a 1:1 ratio of CBD to THC helped relieve pain and trouble sleeping.

Meanwhile, the results of the study, which examined the interaction between cannabinoids and cannabinoid receptors, showed how the endocannabinoid system can regulate appetite.

The powerful anti-inflammatory properties of CBD were also demonstrated in a 2018 study published in the Journal of Experimental Pharmacology and Therapeutics.

By working directly with the body’s cannabinoid receptors to help suppress inflammation, CBD can help people with myocarditis relieve pain and reduce signs and symptoms.

Myocarditis is inflammation of the heart muscle that can cause an irregular heartbeat.

CBD Side Effects

Although CBD has shown potential benefits for cardiovascular disease, there are still risks to consider when taking CBD.

Some of the known side effects of CBD include:

  • dry mouth
  • Diarrhea
  • fatigue
  • lack of appetite
  • drowsiness
  • Other side effects of CBD can also include nausea and pain or an upset stomach.

There are potential drug interactions between CBD and other medications. CBD can increase or decrease the breakdown of some medications in the liver, resulting in overdose or a lack of desired medicinal effects.

First-time CBD users are advised to start slowly with a low dose of CBD. Above all, the advice of a doctor is recommended before using CBD products.

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