With the rising trend of cannabidiol CBD oil in North America, the use of cannabidiol CBD continues to increase, and the types of cannabidiol (CBD) oil products currently available on the market are also increasing. The fundamental difference between different product types of cannabidiol (CBD) oil is the different methods of use, and the absorption of different methods of use is also different. So how can such expensive cannabidiol CBD oil be used more economically? Today, I will bring you the most complete CBD product strategy!
The bioavailability of products with different methods of use is different. Bioavailability refers to the degree and speed of the substance being absorbed by the blood after any treatment in the body, which determines the absorption of the product in the human body. Therefore, the best way to use it is an intravenous injection, and the absorption rate of this method is 100%. However, almost no one will use CBD in this way with needles.
Common uses for cannabidiol CBD oil include:
Oral: capsules, foods, concentrates, etc.
The most common way to use CBD is oral, which means swallowing capsules or consuming its edibles. When CBD is swallowed, it is absorbed into the digestive system, and after being processed by the liver and other digestive organs, only a portion of the CBD passes through these organs into the bloodstream before it can be utilized by the endocannabinoid system.
Through numerous studies, the bioavailability of oral CBD is usually between 10%-20%, and some studies have even found it to be as low as 6%. Whichever study is more accurate, the bioavailability of oral CBD is extremely low which is the reason Cannabidiol(CBD) oil is expensive. However, scientists are currently researching a series of CBD products that can improve the bioavailability of oral CBD, such as water-soluble CBD. It is hoped that there will be more convenient and efficient oral CBD products shortly.
Sublingual administration:
Tinctures, sprays, etc.
The method is to place the CBD in the right place (under the tongue) for the right time (30 to 60 seconds). This method has higher bioavailability than simply swallowing these same CBDs.
There are veins called sublingual glands under the human tongue. When CBD is placed in the sublingual glands, some of it will be directly absorbed into the blood through the sublingual glands, and the rest of the swallowed part will be digested by the liver just like the oral method. Sublingual glands absorb faster and more efficiently, reaching the bloodstream without being metabolized by the digestive system.
Sublingual bioavailability is typically 13%-19%, and some studies suggest it is as high as 35%!
For intranasal use:
Electronic cigarettes, vaporizers, etc.
Inhalation of CBD is the more common way of administering CBD directly into the bloodstream—after inhaling CBD, it can enter the bloodstream from the lungs almost immediately, allowing it to spread and interact with appropriate endocannabinoid receptors throughout the body. Numerous research reports show that the bioavailability of CBD inhaled in the lungs is 34%-46%, and there are even reports that its utilization rate is as high as 56%. Therefore, at present, the method of pulmonary inhalation is the most effective way of ingestion.
Topical use:
Masks, lotions, etc.
Applying cannabidiol directly to the skin is another popular way to use CBD. There are many topical CBD masks, lotions, oils, and other topical products on the market that are designed to relieve symptoms, including pain and skin problems. This application method is feasible, the scientists pointed out that they also found cannabinoid receptors in the skin, and the more water-soluble CBD will make the CBD more easily absorbed by the skin. Therefore, CBD can enter the bloodstream through patches placed on the skin.
The mode of dermal delivery is particularly useful for chronic inflammation, and pain management in chronic pain patients who do not respond well to conventional drug options. In addition, this method of administration is more comfortable than other methods, so many patients with such diseases are more likely to use dermal delivery.
Factors Affecting CBD Absorption
State of health
Since the liver plays an important role in the absorption and processing of CBD in the circulatory system, liver damage will have a significant impact on the absorption rate of CBD. Studies have shown that participants with moderate to severe hepatic insufficiency have higher blood CBD concentrations at the same CBD dose level compared to healthy individuals, suggesting that these individuals use and absorb better than healthy individuals!
In addition to this, neurological disorders or other health conditions may also affect the bioavailability of CBD. The experiment found that at the same dose, the absorption rate of Huntington patients was much lower than that of healthy people.
Recommended dosage
By taking larger CBD doses, it is possible to drive more absorption of CBD, but studies have shown that when the dose reaches between 400mg-800mg, there seems to be a ceiling effect, and higher doses do not lead to higher absorption rates.
CBD Potential Side Effects
The vast majority of people tolerate the use of CBD products well with few side effects. However, users of CBD products must understand that CBD may have the following side effects: dry mouth, diarrhea, loose stools, changes in appetite, fatigue, etc. If these conditions occur after use, please use them as appropriate.
Finally
Although CBD oil is non-toxic, an overdose may occur when one or more other drugs are taken at the same time. Please keep in mind that for your health, please consult a professional doctor before use.
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